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Table 6 Summary of significant normalized and non-normalized thionin (TH) DCX, SMI-32, Calb and Calr cell counts, age, brain and body weight and height correlations in DS and NTD

From: Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome

NTD Age Brain weight Body weight Height DS Age Brain weight Body weight Height
SG TH − 0.80a
0.006b
− 0.78
0.009
− 0.75
0.016
− 0.85
0.0004
  − 0.82
0.0015
− 0.86
2 × 10−7
ns ns
IG TH ns ns ns ns   − 0.84
2 × 10−7
− 0.77
0.007
ns ns
SG DCX − 1.00
2 × 10−7
− 0.98
2 × 10−7
− 0.98
2 × 10−7
− 0.92
2 × 10−7
  ns − 0.91
2 × 10−7
− 0.78
0.005
ns
IG DCX − 0.88
2 × 10−7
− 0.87
2 × 10−7
− 0.90
2 × 10−7
− 0.85
0.0004
  ns − 0.82
0.0015
ns ns
IG SMI-32 0.91
2 × 10−7
0.88
2 × 10−7
0.83
0.002
0.83
0.002
  ns ns ns ns
SG DCX/SG TH − 0.97
2 × 10−7
− 0.95
2 × 10−7
− 0.98
2 × 10−7
− 0.85
0.0004
  ns ns ns ns
IG DCX/IG TH − 0.97
2 × 10−7
− 0.95
2 × 10−7
− 0.98
2 × 10−7
− 0.85
0.0004
  ns ns ns ns
IG SMI-32/IG TH 0.91
2 × 10−7
0.89
2 × 10−7
0.83
0.002
0.83
0.002
  ns ns ns ns
SG Calb/SG TH 0.88
2 × 10−7
0.92
2 × 10−7
0.87
2 × 10−7
0.73
0.02
  ns ns ns ns
SG Calr/SG TH 0.76
0.016
ns 0.82
0.004
ns   ns ns ns ns
  1. ns, not significant
  2. aSpearman’s rank correlation coefficient (r)
  3. bFDR: NTD alpha < 0.02 and DS alpha < 0.007