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Table 6 Summary of significant normalized and non-normalized thionin (TH) DCX, SMI-32, Calb and Calr cell counts, age, brain and body weight and height correlations in DS and NTD

From: Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome

NTD

Age

Brain weight

Body weight

Height

DS

Age

Brain weight

Body weight

Height

SG TH

− 0.80a

0.006b

− 0.78

0.009

− 0.75

0.016

− 0.85

0.0004

 

− 0.82

0.0015

− 0.86

2 × 10−7

ns

ns

IG TH

ns

ns

ns

ns

 

− 0.84

2 × 10−7

− 0.77

0.007

ns

ns

SG DCX

− 1.00

2 × 10−7

− 0.98

2 × 10−7

− 0.98

2 × 10−7

− 0.92

2 × 10−7

 

ns

− 0.91

2 × 10−7

− 0.78

0.005

ns

IG DCX

− 0.88

2 × 10−7

− 0.87

2 × 10−7

− 0.90

2 × 10−7

− 0.85

0.0004

 

ns

− 0.82

0.0015

ns

ns

IG SMI-32

0.91

2 × 10−7

0.88

2 × 10−7

0.83

0.002

0.83

0.002

 

ns

ns

ns

ns

SG DCX/SG TH

− 0.97

2 × 10−7

− 0.95

2 × 10−7

− 0.98

2 × 10−7

− 0.85

0.0004

 

ns

ns

ns

ns

IG DCX/IG TH

− 0.97

2 × 10−7

− 0.95

2 × 10−7

− 0.98

2 × 10−7

− 0.85

0.0004

 

ns

ns

ns

ns

IG SMI-32/IG TH

0.91

2 × 10−7

0.89

2 × 10−7

0.83

0.002

0.83

0.002

 

ns

ns

ns

ns

SG Calb/SG TH

0.88

2 × 10−7

0.92

2 × 10−7

0.87

2 × 10−7

0.73

0.02

 

ns

ns

ns

ns

SG Calr/SG TH

0.76

0.016

ns

0.82

0.004

ns

 

ns

ns

ns

ns

  1. ns, not significant
  2. aSpearman’s rank correlation coefficient (r)
  3. bFDR: NTD alpha < 0.02 and DS alpha < 0.007