Table 2 Summary of molecular characteristics of cases of our series
From: The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile
Case | MC of the sarcoma classifier v12.2 (calibrated score) | MC of the brain classifier v12.5 (calibrated score) | GJA4 status (variant allele frequency) |
|---|---|---|---|
1 | No match | Meningioma subtype benign subclass 3 (0.87) | pGly41Cys mutation (8%) |
2 | No match | Meningioma subtype benign subclass 3 (0.47) | pGly41Cys mutation (10%) |
3 | Lipoma (0,33) | Plexiform neurofibroma (0.46) | pGly41Cys mutation (14%) |
4 | Angiomatoid fibrous histiocytoma (0.99) | Chordoma (0.30) | WT |
5 | NA | NA | NA |
6 | Angioleiomyoma/myopericytoma (0.30) | Meningioma subtype benign subclass 3 (0.78) | WT |
7 | Well/dedifferentiated liposarcoma (0.41) | Plexiform neurofibroma (0.49) | WT |