Fig. 3

Olig2 immunoreactivities in the GE of FASD and control brains. Lower densities of Olig2 expressing cells in the GE of FASD brain at 15 WG by comparison with the GE of control brain at 16 WG in which more than 50% of Olig2 positive cells were observed (a, b) the most striking differences between FASD and control GE being observed at 22 WG (c, d). Similar differences, though less pronounced, were also noted at 24 WG in the FASD brain (case 5) compared to the control (e, f) contrary to what was noted in the FASD brain (case 6), in which an intense immunoreactivity was observed arguing for a delayed production/differentiation starting from this term (g, h)