Variables | Non-recur | Recur | p | NF2 | Non–NF2 | p | Supratent | Infratent | p | Sup. NF2 | Inf. NF2 | Sup. nNF2 | Inf. nNF2 | p | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
In all tumor | N = 281 | N = 236 | N = 45 | N = 150 | N = 131 | N = 188 | N = 93 | N = 109 | N = 44 | N = 79 | N = 49 | ||||
5-yr PFS | 83.4% | 77.9% | 90.3% | 0.04 | 82.1% | 86.7% | 0.18 | 72.8% | 94.1% | 95.3% | 80.6% | 6.2 × 10–4 | |||
GTR | 236 (84.0%) | 209 (88.6%) | 27 (60.0%) | 1.5 × 10–5 | 132 (88.0%) | 104 (79.3%) | 0.19 | 158 (84.0%) | 78 (83.9%) | 1.0 | 91 (83.5%) | 41 (93.2%) | 67 (84.8%) | 37 (75.5%) | 0.04 |
NF2 | 152 (54.1%) | 121 (51.3%) | 31 (68.9%) | 0.03 | 109 (58.0%) | 43 (46.2%) | 0.07 | ||||||||
Supratent | 188 (66.9%) | 152 (64.4%) | 36 (80.0%) | 0.05 | 109 (72.7%) | 79 (60.3%) | 0.07 | ||||||||
Ki-67 index | 2.5 ± 2.0 | 2.2 ± 1.6 | 3.7 ± 3.2 | 0.01 | 2.9 ± 2.4 | 2.0 ± 1.4 | 0.004 | 2.7 ± 2.3 | 2.0 ± 1.3 | 0.02 | 3.2 ± 2.6 | 2.2 ± 1.4 | 2.0 ± 1.5 | 1.8 ± 1.2 | 8.4 × 10–5 |
In GTR | N = 236 | N = 209 | N = 27 | N = 131 | N = 105 | N = 158 | N = 78 | N = 90 | N = 42 | N = 68 | N = 36 | ||||
5-yr PFS | 86.9% | 81.5% | 94.1% | 0.02 | 84.4% | 93.1% | 0.01 | 77.3% | 93.8% | 94.4% | 92.3% | 6.2 × 10–3 | |||
NF2 | 131 (55.5%) | 110 (52.6%) | 21 (77.8%) | 0.01 | 90 (57.0%) | 41 (52.6%) | 0.57 | ||||||||
Supratent | 158 (66.9%) | 133 (63.6%) | 25 (92.6%) | 0.001 | 90 (68.7%) | 68 (64.8%) | 0.57 | ||||||||
Ki-67 index | 2.5 ± 2.0 | 2.3 ± 1.6 | 4.3 ± 3.4 | 0.002 | 2.8 ± 2.3 | 2.1 ± 1.4 | 0.008 | 2.7 ± 2.3 | 2.0 ± 1.2 | 0.03 | 3.2 ± 2.6 | 2.1 ± 1.3 | 2.2 ± 1.6 | 1.8 ± 1.2 | 0.01 |
In STR | N = 45 | N = 27 | N = 18 | N = 20 | N = 25 | N = 30 | N = 15 | N = 18 | N = 2 | N = 12 | N = 13 | ||||
5-yr PFS | 65.4% | 55.6% | 75.1% | 0.21 | 69.3% | 58.2% | 0.61 | 50.0% | 100% | 100% | 51.3% | 0.05 | |||
NF2 | 20 (44.4%) | 10 (37.0%) | 10 (55.6%) | 0.2 | 18 (60.0%) | 2 (13.3%) | 0.004 | ||||||||
Supratent | 30 (66.7%) | 19 (70.4%) | 11 (61.1%) | 0.53 | 18 (90.0%) | 12 (48.0%) | 0.004 | ||||||||
Ki-67 index | 2.3 ± 2.1 | 1.9 ± 1.7 | 2.8 ± 2.7 | 0.42 | 3.3 ± 2.6 | 1.5 ± 1.2 | 0.01 | 2.4 ± 2.3 | 2.0 ± 1.7 | 0.6 | 3.3 ± 2.6 | 3.5 ± 3.5 | 1.2 ± 0.9 | 1.7 ± 1.4 | 0.1 |