Variable | N = 281 | Non–recurrent (N = 236) | Recurrent (N = 45) |
---|---|---|---|
Age | 57.4 ± 13.2 | 58.4 ± 12.4 | 52.5 ± 16.2 |
Sex | Female: 209 (74.4%) | Female: 181 (76.7%) | Female: 28 (62.2%) |
Follow–up (years) | 5.3 ± 4.5 | 5.6 ± 4.6 | 4.1 ± 3.7 |
Tumor location | |||
Supratentorial lesion | 188 (66.9%) | 152 (64.4%) | 36 (80.0%) |
Infratentorial lesion | 93 (33.1%) | 84 (35.6%) | 9 (20.0%) |
Extent of resection | |||
GTR | 236 (84.0%) | 209 (88.6%) | 27 (60.0%) |
STR | 45 (16.0%) | 27 (11.4%) | 18 (40.0%) |
Ki-67 index | 2.5 ± 2.0 | 2.2 ± 1.6 | 3.7 ± 3.2 |
Driver gene mutation | |||
“NF2” (NF2 variant or 22q loss) | 152 (54.1%) | 121 (51.3%) | 31 (68.9%) |
“Non-NF2” | 129 (45.9%) | 115 (48.7%) | 14 (31.1%) |
Subgroups encompassing driver gene mutation and tumor location | |||
“Supratentorial NF2” | 109 (38.8%) | 79 (33.5%) | 30 (66.7%) |
“Infratentorial NF2” | 43 (15.3%) | 42 (17.8%) | 1 (2.2%) |
“Supratentorial non–NF2” | 79 (28.1%) | 73 (30.9%) | 6 (13.3%) |
“Infratentorial non-NF2” | 50 (17.8%) | 42 (17.8%) | 8 (17.8%) |