Table 3 Cortical microglial percentage areas with and without co-morbid diseases and neurodegenerative protein accumulations
Full sample (n = 254) | CD68 |  | CD163 |  | Iba1 |  | |||
|---|---|---|---|---|---|---|---|---|---|
With condition | Without condition | p | With condition | Without condition | p | With condition | Without condition | p | |
HTN | 0.0751 [0.0389,0.1278] | 0.1059 [0.0603,0.1799] | 0.0017 | 0.0361 [0.0222,0.0680] | 0.0535 [0.0279,0.0877] | 0.0212 | 1.0889 [0.6399,1.8770] | 1.3454 [0.6705,2.0336] | 0.1165 |
Diabetes | 0.0761 [0.0386,0.1236] | 0.1045 [0.0542,0.1766] | 0.0109 | 0.0426 [0.0275,0.0811] | 0.0454 [0.0243,0.0767] | 0.6317 | 0.9892 [0.5738,1.5882] | 1.3648 [0.6805,2.0385] | 0.0054 |
Hepatitis | 0.0928 [0.0538,0.1555] | 0.0958 [0.0400,0.1689] | 0.5971 | 0.0420 [0.0250,0.0767] | 0.0484 [0.0273,0.0780] | 0.4024 | 1.2183 [0.6609,2.0385] | 1.1696 [0.6526,1.8135] | 0.4450 |
APOE \(\upvarepsilon\)4 | 0.1073 [0.0554,0.1775] | 0.0861 [0.0497,0.1638] | 0.3147 | 0.0512 [0.0262,0.0822] | 0.0420 [0.0255,0.0750] | 0.3912 | 1.1969 [0.6358,2.0196] | 1.1966 [0.6683,1.9456] | 0.9813 |
A\(\upbeta\) plaques | 0.0820 [0.0392,0.1565] | 0.0983 [0.0566,0.1715] | 0.0956 | 0.0470 [0.0294,0.0775] | 0.0420 [0.0238,0.0764] | 0.6610 | 1.1041 [0.6575,1.7180] | 1.2220 [0.6566,2.0110] | 0.3744 |
Neuronal p-tau | 0.1022 [0.0480,0.1979] | 0.0912 [0.0512,0.1564] | 0.3734 | 0.0447 [0.0258,0.0958] | 0.0442 [0.0260,0.0734] | 0.6174 | 1.2106 [0.7226,2.3159] | 1.1979 [0.6431,1.9511] | 0.6318 |
sub-sample excluding HIV-D (n = 154) | |||||||||
HTN | 0.0716 [0.0353,0.1203] | 0.0871 [0.0487,0.1478] | 0.1582 | 0.0358 [0.0228,0.0700] | 0.0484 [0.0244,0.0706] | 0.6521 | 1.0889 [0.6383,1.8554] | 1.1207 [0.6275,1.7292] | 0.8082 |
Diabetes | 0.0736 [0.0377,0.1258] | 0.0825 [0.0475,0.1258] | 0.5895 | 0.0414 [0.0277,0.0778] | 0.0356 [0.0204,0.0677] | 0.1392 | 0.9165 [0.5469,1.4358] | 1.2040 [0.6767,1.8008] | 0.0601 |