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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Integrated proteomic analysis of low-grade gliomas reveals contributions of 1p-19q co-deletion to oligodendroglioma

Fig. 5

A Volcano plots showing differentially expressed proteins identified between Type I, Type II, and Type III LGG. B List of subtype specific proteins identified through differential protein analysis. Upregulated proteins are in red and downregulated proteins are in blue. C Boxplots comparing the protein expression of glioma and subtype specific proteins between normal brain and the 3 LGG subtypes. p-values correspond to * > 0.05, ** > 0.01, *** > 0.001. D AUC-ROC curves for the classification of LGG subtypes based upon the list of subtype specific proteins. Curves was generated using multinomial regression and tenfold cross-validation. E Upregulated protein pathways in subtype specific proteins in Type I and Type III LGG

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