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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Fig. 4

Number of reactive astrocytes as labelled by GFAP antibody were significantly higher in the temporal pole and visual cortex of demented but not resilient when compared to control brains (a). Representative photomicrographs of GFAP + astrocytes on sections from control, resilient and demented cases containing temporal pole are displayed on the right (b). C Control (Braak 0-II); R Resilient (Braak III/IV); D Demented (Braak III/IV); **p < 0.01; ****p < 0.0001. Scale bar 50 μm

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