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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Fig. 3

Quantifications for total IBA1 burden (percentage of cortex or white matter covered by IBA1 + microglia), total number of astrocytes (ALDH1L1), and total number of oligodendrocytes (Olig2) in temporal and visual cortex (microglia and astrocytes) and white matter (microglia and oligodendrocytes) (b) did not show statistically significant differences between demented, resilient and control brains. Representative photomicrographs of IBA1 + microglia, ALDH1L1 + astrocytes and OLIG2 + oligodendrocytes on sections from control, resilient and demented cases containing temporal pole are displayed on the top (a). C Control (Braak 0-II); R Resilient (Braak III/IV); D Demented (Braak III/IV). Scale bar 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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