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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Fig. 2

Regional Aβ plaque burden (defined as the percentage of cortex occupied by amyloid beta (Aβ) deposits immunostained with 4G8 antibody) (a) and number of neurofibrillary tangles (as reported by immunolabeling with AT8 antibody) (b, c) did not significantly differ in demented compared to resilient. Representative photomicrographs of plaques (a) and tangles (b, c) on sections from control, resilient and demented cases containing temporal pole (a and b) and visual cortex (c). C Control (Braak 0-II); R Resilient (Braak III/IV); D Demented (Braak III/IV); *p < 0.05; **p < 0.01. Scale bars 100 μm and 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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