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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Fig. 1

Example of the artificial intelligence based semiautomated quantification method used. Selection of cortical and subcortical regions of interest (a, b), tissue layer detection in green (b, c, f), P2RY12 counter in purple (c, d), IBA1 area detector in blue (f, g) and unannotated images stained with P2RY12 (e) and IBA1 (h)

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