Table 2 Methylation class and copy number variation of meningiomas
From: Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management
Variables | Overall, N = 62a | Chordoid, N = 11a | Non-Chordoid, N = 51a | p valueb |
|---|---|---|---|---|
MC class, n (%) | < 0.001 | |||
Benign | 16 (26) | 9 (82) | 7 (14) | |
Intermediate | 28 (45) | 1 (9.1) | 27 (53) | |
Malignant | 18 (29) | 1 (9.1) | 17 (33) | |
1p Loss, n (%) | 45 (73) | 7 (64) | 38 (75) | 0.47 |
2p Loss, n (%) | 5 (8.1) | 3 (27) | 2 (3.9) | 0.035 |
10 Loss, n (%) | 15 (24) | 1 (9.1) | 14 (27) | 0.27 |
14q Loss, n (%) | 31 (50) | 1 (9.1) | 30 (59) | 0.003 |
22q Loss, n (%) | 44 (71) | 2 (18) | 42 (82) | < 0.001 |