Fig. 5
From: Impact of APOE genotype on prion-type propagation of tauopathy
Comparative analysis of intrahippocampal pathology in PS19 mice carrying human APOE alleles or murine Apoe. Graphical representation of AT8 immunoreactivity levels in bigenic PS19 mice carrying human APOE alleles from the B6N2 and B6N1 generations and parental PS19 mice carrying mouse Apoe allele. N1 (B6N1) and N2 (B6N2) refer to two subsequent generations with slightly different mouse genetic backgrounds. AT8 burden from PBS injected mice (a, c, e) and K18-tau aggregate seeded mice (b, d, f) shown from three different PS19xAPOE cohorts. Data originally shown in Fig. 2, S8 and S9