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Table 1 Body weights, body mass index, body length and muscle weights

From: Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis

Parameter

3 weeks

6 months

12 months

WT

DMD

WT

DMD

WT

DMD

Body weight (g)

96.9 ± 21.4

76.0 ± 3.4

621.3 ± 38.4

547.2 ± 60.0*

731.1 ± 63.3

337.7 ± 88.9***

Body Mass Index (g/cm2)

0.39 ± 0.03

0.34 ± 0.03

0.70 ± 0.06

0.63 ± 0.04

0.74 ± 0.04

0.34 ± 0.22**

Body length (cm)

15.7 ± 1.2

14.9 ± 0.6

29.1 ± 1.0

29.0 ± 1.3

30.5 ± 1.1

29.6 ± 0.7

Tibialis anterior (g)

0.16 ± 0.03

0.12 ± 0.01

1.21 ± 0.34

0.97 ± 0.22

1.15 ± 0.05

0.55 ± 0.21**

Heart (g)

0.47 ± 0.06

0.47 ± 0.05

1.77 ± 0.10

1.84 ± 0.48

1.86 ± 0.11

2.20 ± 0.45§

Soleus (g)

0.054 ± 0.03

0.035 ± 0.02

0.39 ± 0.03

0.25 ± 0.13

0.35 ± 0.10

0.15 ± 0.06*

  1. p value are calculated refered to WT
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. §p = 0.07