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Table 1 Body weights, body mass index, body length and muscle weights

From: Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis

Parameter 3 weeks 6 months 12 months
WT DMD WT DMD WT DMD
Body weight (g) 96.9 ± 21.4 76.0 ± 3.4 621.3 ± 38.4 547.2 ± 60.0* 731.1 ± 63.3 337.7 ± 88.9***
Body Mass Index (g/cm2) 0.39 ± 0.03 0.34 ± 0.03 0.70 ± 0.06 0.63 ± 0.04 0.74 ± 0.04 0.34 ± 0.22**
Body length (cm) 15.7 ± 1.2 14.9 ± 0.6 29.1 ± 1.0 29.0 ± 1.3 30.5 ± 1.1 29.6 ± 0.7
Tibialis anterior (g) 0.16 ± 0.03 0.12 ± 0.01 1.21 ± 0.34 0.97 ± 0.22 1.15 ± 0.05 0.55 ± 0.21**
Heart (g) 0.47 ± 0.06 0.47 ± 0.05 1.77 ± 0.10 1.84 ± 0.48 1.86 ± 0.11 2.20 ± 0.45§
Soleus (g) 0.054 ± 0.03 0.035 ± 0.02 0.39 ± 0.03 0.25 ± 0.13 0.35 ± 0.10 0.15 ± 0.06*
  1. p value are calculated refered to WT
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. §p = 0.07
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Acta Neuropathologica Communications

ISSN: 2051-5960

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