Skip to main content
Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change

Fig. 3

Representative images of cortical tau pathology in Case 3, a 73-year-old male, former rugby player, with known high-stage CTE-NC from the original diagnostic evaluation. In the section stained for PHF-1 extensive, confluent cortical staining is present within neuronal and astrocytic profiles with no particular cortical distribution discernible (a, c). In contrast, in an adjacent section stained for 4R tau, patchy cortical staining is evident, showing concentration to the depths of cortical sulci, consistent with the pathognomonic lesion of CTE-NC (b, d). Scale bars: a-b 1 mm; c-d main panels, 250 µm; c-d insets, 50 µm

Back to article page