Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment

Table 1 Summary of clinical and pathological data

Case	Gender	Age (years)	Brain weight (g)	Demented	Braak stage [15]	CERAD stage [36, 50]	Hippocampal TDP43 pathology [44, 53]	Other pathology
1	Female	71	1050	No	0	0	No	No
2	Male	66	1350	No	0	0	No	No
3	Male	69	n.a	No	0	0	No	No
4	Male	62	1350	No	0	0	No	No
5	Male	69	1550	No	I	A	No	No
6	Female	86	1000	Yes	II	0	No	Diabetes, Argyrophilic grain disease
7	Female	77	1200	No	III	A	No	No
8	Male	64	1160	No	III	A	No	Argyrophilic grain disease
9	Female	85	n.a	n.a	III	A	No	No
10	Female	86	1040	Yes	III	B	No	No
11	Female	77	1116	No	IV	B	No	No
12	Female	74	960	Yes	V	C	No	No
13	Female	85	1020	Yes	V	C	No	No
14	Male	76	1350	Yes	V	C	No	No
15	Female	83	1050	Yes	VI	C	Yes	No
16	Female	80	930	Yes	VI	C	No	Korsakow syndrom
17	Male	71	1200	Yes	VI	C	No	No

ISSN: 2051-5960