Skip to main content

Table 2 Scoring of CNS pathology in P14 naïve, IgR and AIRlow mice

From: Zika virus vertical transmission in interferon receptor1-antagonized Rag1−/− mice results in postnatal brain abnormalities and clinical disease

Pup ID Treatment Brain Neuronal degeneration, cell death Spinal cord Neuronal degeneration, cell death Spinal cord axonal degeneration
XZ395P1 naïve 0 0 0
XZ395P2 naïve 0 0 0
XZ395P3 naïve 0 0 0
XZ388P4 IgR 0 0 0
XZ388P5 IgR 0 0 0
XZ388P6 IgR 0 0 0
XZ388P7 IgR 0 0 0
XZ389P4 IgR 0 0 0
XZ389P5 IgR 0 0 0
XZ389P6 IgR 0 0 0
XZ389P7 IgR 0 0 0
XZ390P4 IgR 0 0 0
XZ390P5 IgR 0 0 0
XZ392P1 AIRlow 3 2 2
XZ393P1 AIRlow 3 2 2
XZ393P2 AIRlow 1 2 2
  1. Scoring of brain tissue pathology in P14 mice. H&E-stained tissue samples were evaluated in detail and the following scoring system was applied: 0 = no lesions; 1 (exceedingly rare lesions), 2 (rare, scattered lesions), 3 (moderate numbers of evenly dispersed lesions) or 4 (severe lesions)