|
Pup ID
|
Treatment
|
Brain Neuronal degeneration, cell death
|
Spinal cord Neuronal degeneration, cell death
|
Spinal cord axonal degeneration
|
|---|
|
XZ394P1
|
naïve
|
0
|
0
|
0
|
|
XZ394P2
|
naïve
|
0
|
0
|
0
|
|
XZ394P3
|
naïve
|
0
|
0
|
0
|
|
XZ3601P5
|
IgR
|
0
|
0
|
0
|
|
XZ3601P6
|
IgR
|
0
|
0
|
0
|
|
XZ3601P7
|
IgR
|
0
|
0
|
0
|
|
XZ3611P4
|
IgR
|
0
|
0
|
0
|
|
XZ3611P5
|
IgR
|
0
|
0
|
0
|
|
XZ3611P6
|
IgR
|
0
|
0
|
0
|
|
XZ383P5
|
IgR
|
0
|
0
|
0
|
|
XZ383P6
|
IgR
|
0
|
0
|
0
|
|
XZ384P4
|
IgR
|
1
|
0
|
0
|
|
XZ384P5
|
IgR
|
2
|
0
|
1
|
|
XZ357P4
|
AIRlow
|
2
|
2
|
1
|
|
XZ357P5
|
AIRlow
|
2
|
2
|
1
|
|
XZ357P6
|
AIRlow
|
2
|
3 (ganglion)
|
1
|
|
XZ386P3
|
AIRlow
|
1
|
0
|
1
|
|
XZ387P2
|
AIRlow
|
2
|
1
|
2
|
|
XZ387P3
|
AIRlow
|
1
|
0
|
0
|
- Scoring of brain tissue pathology in P7 mice. H&E-stained tissue samples were evaluated in detail and the following scoring system was applied: 0 = no lesions; 1 (exceedingly rare lesions), 2 (rare, scattered lesions), 3 (moderate numbers of evenly dispersed lesions) or 4 (severe lesions)
