Fig. 3

Southern blot images and estimated repeat lengths. a Representative Southern blot images for 17–17 occipital cortex (Oc. Cx) (lanes 1–10) and cerebellum (Cereb) (lanes 11–20) illustrating the varying degree of instability across brain regions. Each lane represents PCR amplification of ~ 30 g.e. M1 and M2 size markers are DIG VII and VIII, respectively and are shown with the corresponding base pair lengths. b Estimated CCCTCT repeat lengths based on distance migrated relative to the M1 and M2 markers. Repeat size data for each sample are obtained from 36 replicates (individual lanes), each with ~ 30 g.e. input DNA amount