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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia

Fig. 7

Treatment with LXR-receptor agonists rescues axonal LD accumulation caused by loss of Arl6IP1. a Representative confocal images of BODIPY-stained LDs (green) within posterior axon bundles from treated CRISPR Control and Arl6IP1 knockout (KO) larvae. b Graphs represent the mean ± SEM number of LDs per μm2 in CRISPR Control and Arl6IP1 KO larvae. n = 19–34 animals per genotype. Statistics consist of two-way ANOVA with Tukey’s multiple comparisons test

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