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Table 1 Demographic and neuropathological data of human samples

From: Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies

Diagnosis Case Sex Age (years) PMD (hours) Disease score Reported concomitant misfolded protein pathologies*
CTL
  1 F 86 5.7 / /
  2 F 80 17.5 / /
  3 F 89 23.6 / Some senile plaques and NFTs
  4 M 89 32.2 / /
  5 M 80 13.0 / Some senile plaques
  6 F 83 35.7 / /
  7 F 95 23.7 / /
  8 M 85 26.7 / /
  9 M 83 16.8 / /
  10 M 89 31.9 / A1B1C1
  11 F 55 21.1 / /
DLB  
  12 M 70 24.5 Neo-cortical diffuse Senile plaques and NFTs
  13 M 89 17.0 Limbic transitional Mixed AD
  14 M 75 21.0 Neo-cortical Senile plaques and NFTs
  15 M 64 17.2 Neo-cortical Senile plaques and NFTs
  16 F 83 17.7 Neo-cortical Senile plaques and NFTs
  17 M 82 22.0 Neo-cortical diffuse /
  18 F 81 8.6 Neo-cortical diffuse /
  19 F 74 27.6 Neo-cortical A2B2C0
  20 M 91 85.0 Neo-cortical diffuse Braak III/IV
AD  
  21 M 80 15.5 Braak IV /
  22 M 82 11.5 Braak IV /
  23 M 85 31.1 A2B3C2 /
  24 F 83 25.0 A2B3C2 /
  25 M 91 25.0 A2B3C2 /
  26 F 96 26.5 Braak IV/V /
  27 M 87 21.7 A2B3C2 /
  28 M 90 26.1 A3B2C3 /
  29 F 87 17.0 A1B2C2 /
  30 M 90 32.0 A2B2C3 /
  1. AD Alzheimer’s disease, CTLs age-matched controls, DLB Dementia with Lewy Bodies, NFTs neurofibrillary tangles, PMD post-mortem delay
  2. *After neuropathological examination