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Table 1 Demographic and neuropathological data of human samples

From: Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies

Diagnosis

Case

Sex

Age (years)

PMD (hours)

Disease score

Reported concomitant misfolded protein pathologies*

CTL

 

1

F

86

5.7

/

/

 

2

F

80

17.5

/

/

 

3

F

89

23.6

/

Some senile plaques and NFTs

 

4

M

89

32.2

/

/

 

5

M

80

13.0

/

Some senile plaques

 

6

F

83

35.7

/

/

 

7

F

95

23.7

/

/

 

8

M

85

26.7

/

/

 

9

M

83

16.8

/

/

 

10

M

89

31.9

/

A1B1C1

 

11

F

55

21.1

/

/

DLB

 
 

12

M

70

24.5

Neo-cortical diffuse

Senile plaques and NFTs

 

13

M

89

17.0

Limbic transitional

Mixed AD

 

14

M

75

21.0

Neo-cortical

Senile plaques and NFTs

 

15

M

64

17.2

Neo-cortical

Senile plaques and NFTs

 

16

F

83

17.7

Neo-cortical

Senile plaques and NFTs

 

17

M

82

22.0

Neo-cortical diffuse

/

 

18

F

81

8.6

Neo-cortical diffuse

/

 

19

F

74

27.6

Neo-cortical

A2B2C0

 

20

M

91

85.0

Neo-cortical diffuse

Braak III/IV

AD

 
 

21

M

80

15.5

Braak IV

/

 

22

M

82

11.5

Braak IV

/

 

23

M

85

31.1

A2B3C2

/

 

24

F

83

25.0

A2B3C2

/

 

25

M

91

25.0

A2B3C2

/

 

26

F

96

26.5

Braak IV/V

/

 

27

M

87

21.7

A2B3C2

/

 

28

M

90

26.1

A3B2C3

/

 

29

F

87

17.0

A1B2C2

/

 

30

M

90

32.0

A2B2C3

/

  1. AD Alzheimer’s disease, CTLs age-matched controls, DLB Dementia with Lewy Bodies, NFTs neurofibrillary tangles, PMD post-mortem delay
  2. *After neuropathological examination