Fig. 6From: Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodiesMicroglial morphological features and clusters correlate with pTau, Aβ, and pSyn burdens in the hippocampus and follow a subregional pattern. Correlation plots between pathologies and microglial morphological features (a–c) and morphological clusters (d–f) in CA1, CA3 and DG/CA4 in CTL, AD and DLB conditions. A list and description of all morphological features with prototypic morphologies for lowest and highest value can be found in Additional file 1: Fig. S3 online resource). a–c Various microglia morphological changes are correlated to one or two AD and DLB pathologies in a subregion-dependent manner. d–f In a subfield-dependent manner, disease-enriched clusters 3 and 5 are positively correlated with one or two pathologies whereas disease-depleted cluster 7 present negative correlations. Statistically significant values (Spearman’s correlation) are indicated by a dot, the colour gives an estimation of the correlation (positive correlations in blue, negative correlations in red). Black crosses indicate unsignificant correlationsBack to article page