Table 1 Immunostains from primary and recurrent resection
From: Thoracic low grade glial neoplasm with concurrent H3 K27M and PTPN11 mutations
Marker | Primary | Recurrent |
|---|---|---|
GFAP | Diffusely, strongly positive | Diffusely, strongly positive |
CD44 | Diffusely, strongly positive | – |
PDGFRA | Weakly positive in a subset | – |
SOX2 | Positive in majority of tumor cells | Positive in majority of tumor cells |
OLIG2 | Positive in a subset | Positive in a subset (~ 20%) |
SOX10 | – | Positive in a subset (~ 20%) |
IDH1 R132H | Negative | – |
ATRX | Preserved | – |
PTEN | Negative | – |
TP53 | Rare cells | – |
H3 K27M | Positive | Positive |
KI67 | Up to 2.8% | Up to 2.4% |