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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Thoracic low grade glial neoplasm with concurrent H3 K27M and PTPN11 mutations

Fig. 1

Initial presentation and histopathology of primary resection. a, b Initial sagittal T2 MRI (a) and repeat study 5 months later (b). c, d Hematoxylin and eosin (H&E)-stained sections revealed a glial neoplasm characterized by foci of alternating cellularity (c) and moderate pleomorphism (d). e Relatively rare cells were highlighted with KI67 immunostain. f The nuclei of the tumor cells were diffusely positive for mutant histone protein H3 K27M by immunostaining (for all histology panels, scale bar = 100 µm)

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