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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization

Fig. 4

AD-tau increases CK2 in vitro Immunocytochemistry of CK2 in ADPHF treated hippocampal neurons. Neurons were treated with a PBS or ADPHFs for b 14 or c 7 days in vitro (DIV); scale bar = 50 µm. d Quantification of CK2-positive area was normalized to DAPI positive area. **p < 0.01, ***p < 0.001, one-way ANOVA followed by Tukey post hoc test. Quantification of e nuclear, f cytoplasmic, and g nuclear:cytoplasmic ratio of CK2 normalized to DAPI. *p < 0.05, **p < 0.01, ***p < 0.001, one-way ANOVA followed by Tukey post hoc test. n = 5/group

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