Fig. 4
From: Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease
Relationship between the cerebellar concentration of key metabolites and accelerated rotarod performance on Tg-ATXN3-69Q (MJD) Mice. Linear regression between the cerebellar concentration (mM) of NAA, NAA + NAAG, Glu, Tau and Ins normalized with Cr, as well as NAA/tCho ratio, and the performance of MJD mice of 2 and 4 months of age (n = 22) in accelerated rotarod (sec). *p < 0.05 and ***p < 0.001. Abbreviations: NAA—N-acetylaspartate; NAAG—N-acetylaspartylglutamate; Cr—Creatinine; Glu—Glutamate; Tau—Taurine; Ins—Myo-inositol; tCho—Total Choline. Image created by me or a co-author