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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology

Fig. 5

Deconvolving malignant cell states and their interaction with immune based clusters. A Differential distributions of IDH-WT specific malignant cell-states between the two immune-based survival groups are depicted by boxplots. B Scatter plots representing a positive correlation between the proportions of M0 macrophages and MES-like component of IDH-WT tumors across all 3 datasets. C Scatter plots representing a significant positive correlation between the expressions of OSM from macrophages and OSMR from malignant cells in IDH-WT tumors identified by scRNA based deconvolution. D Boxplots depicting differential distribution of epithelial-mesenchymal transition markers between the two immune-based survival groups. Similarly, E boxplots depicting differential distribution of STAT3 signaling markers between the two immune-based survival groups

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Acta Neuropathologica Communications

ISSN: 2051-5960

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