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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Intratumoural spatial distribution of S100B + folliculostellate cells is associated with proliferation and expression of FSH and ERα in gonadotroph tumours

Fig. 2

The percentage of S100B immunoreactive cells is lower in PitNETs compared to the APG. A Representative images of S100B immunoreactive cells found in the normal APG, and in gonadotroph, corticotroph, and Pit1 PitNETs. Lower panels show an enlarged view of the dashed insets. Scale bars = 20 µm (top), and 100 µm (bottom). B Percentage of S100B + cells in the tumour tissue of 54 PitNETs (median = 0.18%) versus 4 normal APG samples (median = 3.95%). Statistical test: Mann–Whitney, p = 0.003 (**). Graph—median with interquartile range. C Percentage of S100B + cells in matching tumour (median = 0.13%, range 0.00%-3.42%) versus adjacent APG tissue (median = 3.17%, range 1.71–11.68%) from 9 patients (P) with PitNETs. Statistical test: Wilcoxon matched paired test. Abbreviations: human pituitary neuroendocrine tumours (PitNETs), anterior pituitary gland (APG)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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