Fig. 3From: White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognitionThe predicted cognition by age group for a given value of NODDI measure and AD biomarker. The reference (green) lines are predictions for healthy white matter tracts and low AD biomarkers (low amyloid, low tau, high temporal NDI, high Genu NDI, low Genu ISOVF). The blue lines are predictions for poor Genu health (high Genu ISOVF and low Genu NDI) in MCSA. The black lines are predictions for abnormal AD biomarker (high amyloid in MCSA and high tau in ADRC). The abnormal temporal WM (red) lines in ADRC show predictions for low ITWM. In the plot, reference (low) and abnormal (high) are defined by 25th and 75th percentilesBack to article page