Fig. 1
From: White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition
Conceptual diagram illustrating the white matter tracts studied and their biological associations. Top panel: Genu as the white matter tract studied for systemic vascular health; parahippocampal cingulum (CGH) and inferior temporal white matter (ITWM) studied for temporal lobe pathologies. A Association of Genu white matter NODDI measures with systemic vascular health in MCSA. B Association of CGH and ITWM NDI measures with tau deposition in ADRC. Tau values were log transformed. C Association of CGH and ITWM NDI measures with FDG TDP-43 signature in MCSA. Inferior temporal to medial temporal (IMT) and frontal supra orbital ratio (IMT/FSO) was used as FDG TDP-43 signature