Table 6 Selected highest ranking AI feature differences between Parkinson disease and controls (Mann–Whitney U test), and between stages (Kruskal–Wallis test)
AI features | Mann–Whitney U test | |
|---|---|---|
U | p Value | |
PreciseDx Graph Feature27 | 143.0 | 0.001 |
LTS cluster size StDev | 122.0 | 0.001 |
PreciseDx Graph Feature3 | 138.0 | 0.002 |
PreciseDx Graph9 | 170.0 | 0.009 |
StDev of Hematoxylin Channel | 175.5 | 0.025 |
PreciseDx Graph Feature14 | 210.0 | 0.027 |
Calinski-Harabasz index | 179.5 | 0.030 |
PreciseDx Graph Feature13 | 201.5 | 0.047 |
PreciseDx Graph Feature28 | 208.5 | 0.056 |
Davies-Bouldin Index | 204.0 | 0.088 |
PreciseDx Graph Feature11 | 249.0 | 0.338 |
PreciseDx Graph Feature10 | 268.0 | 0.419 |
C index | 266.5 | 0.601 |
LTS pixel fraction | 168.0 | 0.017 |
StDev of DAB channel (brown) | 173.5 | 0.023 |
Number of LTS patches | 153.0 | 0.008 |
Kruskal–Wallis test | ||
|---|---|---|
Kruskal–Wallis H | p Value | |
PreciseDx Graph Feature4 | 11.6 | 0.003 |
PreciseDx Graph Feature17 | 10.9 | 0.004 |
PreciseDx Graph Feature3 | 7.5 | 0.024 |
LTS cluster size StDev | 7.0 | 0.03 |
PreciseDx Graph Feature27 | 4.8 | 0.089 |