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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: A novel LARGE1-AFF2 fusion expanding the molecular alterations associated with the methylation class of neuroepithelial tumors with PATZ1 fusions

Fig. 2

Illustration of the fusion and t-SNE analysis A RNAseq analysis highlights a fusion between LARGE1 (red) and AFF2 (blue) genes, respectively located on chr22q12.3 and chrX.q28 with a breakpoint in exon 6 for LARGE1 and exon 8 for AFF2. B t-distributed stochastic neighbor embedding (t-SNE) analysis of the DNA methylation profile of the investigated tumor alongside 361 selected reference samples

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