Fig. 4

Minocycline does not improve acute post-TBI myelination but alters OPC morphology. a Representative image of myelin black gold staining and b quantification of percentage of myelinated area. c Fluorescent image of PDGFR-α in DG and d quantification of PDGFR-α + cells density. e Representative three-dimensional reconstruction images of PDGFR-α + cells. f–j Quantification of the OPC morphology. f process length, g volume, h number of branch points, i number of segments and, j number of terminal points. Mean values are plotted ± SD, unpaired t test **p < 0.01, n = 8 mice per group