Fig. 5

Comparison in the OS of patients with GBMs enriched in giant cells and TCGA GBMs IDH-wt or IDH-mutant. Patients with giant cells enriched GBM had an OS significantly shorter than patients with IDH-mutant GBM (P = 0.0127), but not significantly different from that of patients with IDH-wt GBM (P = 0.187). Patients with giant cell enriched GBM and younger than 55 years had an OS significantly longer than patients with IDH-wt GBM and similar to patients with IDH-mutant GBM, while those of 55 years or older had an OS length similar to IDH-wt GBM and significantly shorter than IDH-mutant GBM (P = 0.0013)