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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Developmental deficits and staging of dynamics of age associated Alzheimer’s disease neurodegeneration and neuronal loss in subjects with Down syndrome

Fig. 7

Rate of neuronal loss. The speed of neuronal loss is defined by the estimated rate of neuronal loss per day and the number of lost neurons per million neurons/day. Graphs a-c illustrate regional differences in the rate of neuronal loss in the fourth, fifth, and sixth decades of life, respectively, of DS subjects. b and d reveal the top level of the rate of neuronal loss in the fifth decade. The cumulative rate of neuronal loss (number of lost neurons per day in all examined regions) is similar in the fourth and fifth decades (4,318/day and 4,278/day, respectively) but decreases by half in the sixth decade (2,106/day) (e)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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