Fig. 3From: STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networksSTAT3 inhibition rescues the behavioral deficits of 5XE4 mouse model of AD. The cognitive function in experimental mice was assessed by measuring A exploratory preference in novel object recognition test, B exploratory preference in novel object location task, C novel arm entries in Y-maze test, D weight burrowed in burrowing test. Data is presented as mean ± SEM, #,*p < 0.05, #- as compared to veh + WT, *- as compared to veh + 5XE4, n = 9–10 in each group, veh- vehicle, WT- wild-type, 5XE4- 5XFAD/APOE4Back to article page