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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Prion type 2 selection in sporadic Creutzfeldt–Jakob disease affecting peripheral ganglia

Fig. 2

CJD subtype distribution in prion-accumulating and prion-negative peripheral ganglia. Within each figure (AD) the left panel depicts the ganglia that stained positive for prion aggregates, while the right panel shows the ganglia that were tested negative. The abscissa displays the different subtypes of the prion-accumulating and not prion-accumulating ganglia. The ordinate gives the number of corresponding patients. The percentages indicate their respective portion in relation to all ganglia of a certain type (e.g. the trigeminal ganglion, A) investigated. Statistical analysis of ganglion involvement per disease subtype showed a highly significant association for the trigeminal (***p < 0.001) (A) and significant association for the nodose ganglion (*p < 0.05) (B), whereas no statistically significant correlations could be found for the thoracic sympathetic trunk or the celiac ganglia (n.s. p > 0.05) (C, D)

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