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Table 1 List of statistical tests and results for each figure

From: Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein

Figure

Graph identification

Type of test

Statistics

1B

vGLUT1/ α-synuclein

Nested t-test (two-tailed)

t(6) = 2.9, P = 0.0284

1D

LRRK2

One-way ANOVA

F(2,3) = 1.9, P = 0.2896

 

pS1292-LRRK2

One-way ANOVA

F(2,3) = 95.4, P = 0.0019

 

vGLUT1

One-way ANOVA

F(2,3) = 0.3, P = 0.7839

 

α-synuclein

One-way ANOVA

F(2,3) = 1.0, P = 0.4700

2D

vGLUT1/Homer1

Nested t-test (two-tailed)

t(2) = 0.8, P = 0.5135

 

vGLUT1/ α-synuclein

Nested t-test (two-tailed)

t(116) = 6.5, P < 0.0001

3B

Mobile tracks

Nested t-test (two-tailed)

t(6) = 3.4, P = 0.0144

 

Vesicle count

Nested t-test (two-tailed)

t(6) = 0.6, P = 0.5983

 

Anterograde tracks

Nested t-test (two-tailed)

t(51) = 2.2, P = 0.0332

 

Retrograde tracks

Nested t-test (two-tailed)

t(6) = 0.5, P = 0.6570

3D

Anterograde tracks

Nested t-test (two-tailed)

t(6) = 0.4, P = 0.7229

 

Retrograde tracks

Nested t-test (two-tailed)

t(87) = 1.8, P = 0.0785

4A

LRRK2

One-way ANOVA

F(2,3) = 0.3, P = 0.76

 

pS935-LRRK2

One-way ANOVA

F(2,3) = 54.35, P < 0.0001

4B

LRRK2

Mann–Whitney test

P = 0.800

 

pS1292

Mann–Whitney test

P = 0.200

 

DAT

Mann–Whitney test

P = 0.800

 

vGLUT1

Mann–Whitney test

P = 0.400

 

α-synuclein

Mann–Whitney test

P = 0.800

4C

α-synuclein LP2

Independent t-test

t(4) = 1.8, P = NS

5C

vGLUT1/ α-synuclein

Nested t-test (two-tailed)

t(6) = 3.3, P = 0.035

5D

DAT/ α-synuclein

Nested t-test (two-tailed)

t(178) = 6.6, P < 0.0001

6D

vGLUT1/Homer1

Nested t-test (two-tailed)

t(4) = 0.6, P = 0.5685

 

vGLUT1/ α-synuclein

Nested t-test (two-tailed)

t(4) = 5.3, P = 0.0063