Fig. 3

Correlations among αSyn-SAA kinetic parameters across the three assays. a Correlations among maximum fluorescence (F_max), area under the curve (AUC), time to 50% maximum (T₅₀), or time to threshold (TTT) among the three assays for baseline (BL) samples. Diameter of each circle is proportional to strength of correlation (Spearman r), and the color indicates positive (orange) and negative (blue) correlations (**p ≤ 0.01, *p ≤ 0.05). b Similar analysis of correlation for year 3 (Y3) samples. c Correlations of changes in assay kinetic parameters from baseline (BL) to year 3 (Y3). Absolute change (Δ, Y3—BL) was calculated and rank order correlations were determined for each pairing of parameters