Fig. 1From: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s diseaseExperimental design. PD, HC, and SWEDD samples were randomly selected from available PPMI subjects as a pilot study. Aliquots from each subject were distributed to three independent laboratories for αSyn-SAA according to proprietary methods without procedural coordination or communication. αSyn-SAA was performed and initially analyzed in blinded manner with respect to diagnosis. After completion of assays, 2 PD and 2 SWEDD subjects were removed from further analysis due to interval changes in consensus diagnosisBack to article page