Skip to main content
Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson’s disease and dementia with Lewy bodies

Fig. 2

Longitudinal trajectories of RT-QuIC seeding profiles. Out of the 100 PD patients included in this longitudinal analysis, 86 were RT-QuIC seeding positive while 14 did not show seeding. A Linear mixed model analysis in the longitudinal PD cohort with repeated lumbar puncture and RT-QuIC assay measurements revealed that time had no significant impact on the number of positive RT-QuIC seeding replicates over the course of the disease, neither in those patients who were seeding positive nor in those who were seeding negative (p = 0.670). B, C Similarly, RT-QuIC seeding positives showed stable results of Imax (p = 0.558) and LAG phase (p = 0.324) over time

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us