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Fig. 17 | Acta Neuropathologica Communications

Fig. 17

From: Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation

Fig. 17

Perivascular inflammation in the brain of a blast-exposed animal. Panel a shows a brain region with patches of clustered activated microglia (Iba1+, red) next to a vascularized region in between the deep cerebral white matter, choroid plexus and hippocampal fimbria. Insert in a shows higher magnification of a 0.56 µm optical section of the area indicated by arrow. Note the tortuous vessel (arrow). Panel b denotes higher magnification of an artery (identified by * in panel a) with perivascular activated microglia (Iba1+, red). Panels c, d show GFAP+ intracellular material (green) in perivascular activated microglia (Iba1, red; GFAP, green). Scale bar, 200 µm a; 10 µm bd

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