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Fig. 16 | Acta Neuropathologica Communications

Fig. 16

From: Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation

Fig. 16

Perivascular microglia in the brain of blast-exposed animals. Panels ac show clustered Iba 1+ microglia (red, arrow in b) with amoeboid morphology in the perivascular area of a tortuous large vessel (pericallosal artery) in the corpus callosum of a rat brain at 13 months post-blast exposure. Panel d shows an orthogonal projection of a section through a thalamic artery stained for perivascular astrocytes (GFAP+, green) and microglia (Iba1+, red). Co-localization of astrocytic GFAP+ material within a perivascular microglial cell, suggests phagocytic ingestion of perivascular astrocytes by microglia. Scale bar, 100 µm a; 40 µm b; 20 µm c, d

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