Fig. 6
From: TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
Apoptosis signaling is downregulated in AD hippocampus. a Analysis of mRNA levels of the Caspase 3, Caspase 8, cIAP1, and CFLAR genes in the hippocampus grey matter in AD cases (n = 30) and controls (n = 14). b Representative western blots of full-length and cleaved caspase 3 and caspase 8. Full blots are shown in Additional file 6: Fig. 6. Quantification of cleaved caspase 3 and caspase 8 protein levels in AD (n = 15) and control cases (n = 10), normalized to GAPDH. Data are represented as mean ± SEM, **p < 0.01, ***p < 0.001, ****p < 0.0001