Table 1 Demographic characteristics and CSF parameters of healthy controls, CAA patients, and AD patients
From: MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy
|  | Control (n = 37) | CAA (n = 23) | AD (n = 26) | p-Value |
|---|---|---|---|---|
Demographics | ||||
Age, years, mean ± SD | 63.8 ± 8.5 | 70.6 ± 7.8** | 64.3 ± 7.3$ | 0.004 |
Sex (female), n (%) | 11 (29.7%) | 7 (30.4%) | 14 (53.8%) | 0.110 |
CSF parameters, pg/ml | ||||
Aβ40, mean ± SD | 10,187.9 ± 4009.1 | 7911.1 ± 3140.1 | - | 0.032 |
Aβ42, median (IQR) | 895.1 (678–1225) | 360 (317.5–462)*** | 514.6 (468.6–593.5)*** |  < 0.001 |
t-Tau, median (IQR) | 231 (170–317) | 403 (268–512.5)** | 328.6 (183.4–395.3) | 0.002 |
p-Tau, median (IQR) | 28 (19–39) | 45 (33.5–63.5)** | 32.4 (18.1–39.6)$ | 0.001 |
MFG-E8, median (IQR) | 4568.4 (3672.3–5898) | 3345.5 (2661.8–4648.3)* | 5655.6 (4552.6–6849.2)$$$ |  < 0.001 |