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Table 2 Brain regions sampled

From: Anatomic survey of seeding in Alzheimer’s disease brains reveals unexpected patterns

  Regions
1 Transentorhinal cortex (TRE)
2 Entorhinal cortex (EC, Brodmann Area 28)
3 Ammon's horn, sector 1 (CA1, hippocampal formation)
4 Amygdala, basolateral subnucleus (AMY)
5 Superior (first) temporal gyrus (STG, Brodmann Area 22)
6 Transverse temporal gyrus of Heschl (TTG, Brodmann Area 41)
7 Primary visual neocortex (PV, Brodmann Area 17)
8 Peristriate neocortex, high order sensory neocortex (Brodmann Area 19)
9 Anterior cingulate cortex—skeletomotor/emotion-autonomic integration (ACC, Brodmann Areas 24/32)
10 Retrosplenial/posterior cingulate cortex—memory/visuospatial orientation (RSC/PCC, Brodmann Areas 23/29/30)
11 Putamen (PUT)
12 Globus pallidus (GP)
13 Mediodorsal complex of thalamus (MD)
14 Orbitofrontal cortex (OFC, Brodmann Area 11)
15 Substantia nigra, pars compacta (SNpc)
16 Locus coeruleus (LC)
17 Basal nucleus of Meynert(BN)
18 Pontine gray (PG)
19 Inferior olivary nucleus (IO)
20 Cerebellar cortex (CC)
21 Cerebellar dentate nucleus (DN)
22 Internal capsule, anterior limb (IC)
23 Terminal stria (TS)
24 Olfactory bulb (OB)
25 Optic chiasm/tract (OC)
  1. Punch biopsies were made from unstained sections of the 25 brain regions shown above using a 4 mm (3 mm for regions 19 and 22 in Experiment II) punch biopsy tool. Cross-contamination of seeding activity between individuals and regions was prevented by disposing the biopsy tool after each punch