Table 1 Demographic and neuropathological data
From: Anatomic survey of seeding in Alzheimer’s disease brains reveals unexpected patterns
Case | f/m | age | brain wt | NFT | Aβ | α-syn | TDP-43 | APOE | Diagnoses |
|---|---|---|---|---|---|---|---|---|---|
1 | f | 55 | 1455 | I | 0 | 0 | − | ε3/4 | intraventricular hemorrhage |
2 | m | 55 | 1780 | I | 0 | 0 | − | ε3/3 | bronchopneumonia |
3 | f | 50 | 1293 | I | 0 | 0 | − | ε3/3 | PCOM aneurysm, SAB |
4 | m | 50 | 1600 | I | 0 | 0 | − | ε4/4 | M. Werlhof, hepatitis C |
5 | f | 72 | 1070 | I | 3 | 0 | − | ε3/4 | cardiac failure |
6 | f | 79 | 1165 | I | 0 | 0 | − | ε3/3 | coronary artery disease |
7 | f | 93 | 1090 | III (IV) | 2 | 0 | − | na | craniocerebral trauma |
8 | m | 68 | 1380 | III | 0 | 0 | − | na | aspiration pneumonia |
9 | m | 72 | 1500 | III | 0 | 0 | − | ε3/4 | cardiac failure |
10 | m | 74 | 1465 | III | 0 | 0 | − | ε4/4 | malignant neoplasm |
11 | m | 76 | 1520 | III | 4 | 0 | + | na | pneumonia |
12 | f | 81 | 1130 | III | 2 | 0 | − | ε3/3 | acute myeloid leukemia |
13 | f | 88 | 1495 | III | 3 | 0 | − | ε3/4 | cerebral hemorrhage parietooccipital |
14 | m | 84 | 1170 | V (VI) | 3 | 0 | + | ε3/4 | AD |
15 | f | 84 | 1175 | V | 3 | 2 | + | ε3/3 | AD, ILBD |
16 | m | 58 | 1335 | V | 2 | 0 | − | ε3/4 | AD, myocardial infarction |
17 | f | 72 | 1185 | V | 4 | 0 | − | ε3/3 | AD, craniocerebral trauma after falling |
18 | f | 76 | 1405 | V | 4 | 0 | − | ε3/4 | AD, craniocerebral trauma after falling |
19 | m | 76 | 1205 | V | 5 | 0 | − | na | AD, cardiac failure |
20 | m | 78 | 1460 | V | 5 | 0 | − | ε3/4 | AD |
Control 21 | f | 30 | 1315 | 0 | 0 | 0 | − | ε3/3 | malignant neoplasm |