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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Anatomic survey of seeding in Alzheimer’s disease brains reveals unexpected patterns

Fig. 3Fig. 3

Seeding in 20 individuals, 25 brain regions (derived from Experiment I). a Seeding data heat map: Data points below the seeding threshold of 0.35% are colored in gray. Data points equal and above the seeding threshold are shaded with a graded color scale ranging from yellow (low) to red (high). Seeding data from human control brain (tau negative) was included as a comparison. b Seeding data from 25 brain regions plotted as individual graphs and separated according to NFT stage. Individual symbols (dot, square, triangle) represent data from individuals at each NFT stage. Statistical significance was determined by performing a non-parametric rank order test (Whitney-Mann test) to compare NFT I vs. III, III vs. V, and I vs. V. ns = non-significant, *p < 0.05, **p < 0.01. Errors bars show SD

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