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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer’s disease

Fig. 5

Low-grade peripheral inflammation affects Aβ deposition in AppNL-G-F mice. a Representative images of 6E10 staining in hippocampus and cortex of AppNL-G-F mice. Scale bar: 100 μm. b Quantification of Aβ plaque area and number (n = 5–6). Hippocampus (left two graphs); cortex (right two graphs). c Quantification of Aβ plaque size distribution. Hippocampus (left); cortex (right); (n = 5–6). d Soluble and insoluble Aβ1-40 and Aβ1-42 levels in prefrontal cortex tissues (n = 5). Mean ± SEM, two-way ANOVA Bonferroni’s post hoc test for multiple comparisons. *p < 0.05, **p < 0.01

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