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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice

Fig. 7

Aβ plaque burden was differentially affected by TREM2 genotype in male and female AD-tau-injected 5XFAD mice. a Representative image of cortical and subiculum NAB228-positive Aβ plaques in female 5XFAD × TREM2+/+ and 5XFAD × TREM2+/− mice. b Quantification of cortical Aβ plaque burden in AD-tau-injected 5XFAD mice as a function of TREM2 genotype. c Cortical Aβ plaque burden graphed by sex for each TREM2 genotype. Scale bar represents 0.4 mm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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